Hayflick Limit - a manifestation of the law of temporal hierarchies

Gladyshev G. P.

The law of temporal hierarchies [1, 2] is confirmed by many observable patterns. One of such regularities is the Hayflick limit [3,4], which determines the limit of the termination of the division of somatic cells of organisms. In other words, the Leonard Hayflick limit determines the lifespan of somatic cells, one of the hierarchical structures of the living world. Thus, the Hayflick limit is a particular case of the manifestation of the law of temporal hierarchies, which underlies the hierarchical thermodynamics.


1. Gladyshev G.P., Thermodynamics Theory of the Evolution of Living Beings, Commack, New York: Nova Science Publishers, Inc., 1997. 142 P. In Russian: Гладышев Г.П., Термодинамическая теория эволюции живых существ, М.: ”Луч”, 1996.-86с. ISBN 5-7005-0545-2 (пер.)  http://creatacad.org/?id=58&lng=eng 


2. Gladyshev G.P. The time has come to revive and develop the classics: hierarchical thermodynamics and life, Norwegian Journal of development of the International Science, №26/2019, Vol. 2, pp. 15-20. ISSN 3453-9875 http://www.njd-iscience.com/wp-content/uploads/2019/01/NJD_26_2.pdf 

3. Hayflick L,, Moorhead PS (1961). "The serial cultivation of human diploid cell strains", Exp Cell Res. 25 (3): 585–621. doi:10.1016/0014-4827(61)90192-6. PMID 13905658.

4. Hayflick L. (1965). "The limited in vitro lifetime of human diploid cell strains", Exp. Cell Res. 37 (3): 614–636. doi:10.1016/0014-4827(65)90211-9. PMID 14315085.